I work in Waltham, MA where we’re lucky enough to still have a thriving indepedent bookstore that promotes local authors, Back Page Books. See the link at the right to their website.
Small press/self-published authors and independent bookstores seem to me to be natural allies.
In any case, I’m a big fan of this wonderful bookstore, and since I hope to see it be around for a long time to come, I’m doing my small bit to promote it.